Signet software (Agilent Technologies – Silicon Genetics) is a highly scalable analysis platform for managing and mining expression data in a workgroup or an enterprise setting. Signet streamlines microarray research at large and multicampus organizations, and facilities robust data analysis, collaborative workflow management, research procedure automation and secure data administration.
Developed by the Division of Biomedical Informatics at Cincinnati Children's Hospital Medical Center, TraFaC and GenomeTraFaC are companion Java applications that enable researchers to search human and murine sequences for transcription factor binding sites in the phylogenetically conserved regions. Both deliver results in an intuitive, graphical format. While TraFaC is geared toward researchers wanting to upload and analyze their own sequences, GenomeTraFaC is aimed at researchers wanting to search an automatically populated database of more than 7300 human and mouse orthologous gene pairs with a validated RefSeq ID.
Developed by the Division of Biomedical Informatics at Cincinnati Children's Hospital Medical Center, PolyDom is a web-based application used to map Synonymous and Non-synonymous Single-Nucleotide Polymorphisms (SNPs) of proteins onto known functional domains. 3D structures of proteins determine their function. Hence the SNPs are mapped onto the 3D structures wherever an equivalent protein structure is available (PDB). Also the latest PubMed results pertaining to the protein and its SNPs are furnished on the results page. A Polyview link is also given for each of the protein in the database. The SNPs are highlighted in the polyview image for easy inference of the results.